Periodontology Unit and Division of Clinical Research, Eastman Dental Institute and Hospital, University College London (UCL), London, UK.
J Clin Periodontol. 2011 Jan;38(1):50-7. doi: 10.1111/j.1600-051X.2010.01648.x. Epub 2010 Nov 22.
The aim of this retrospective study was to analyse the clinical and radiographic response of infrabony defects following non-surgical therapy and to detect the factors associated with such a response.
Clinical and radiographic data were retrieved from 143 consecutive patients treated with non-surgical periodontal therapy and re-assessed by the same clinician. Linear radiographic measurements of infrabony periodontal defects were performed on baseline and follow-up (12-18 months post-treatment) radiographs. Multilevel analysis was performed to analyse the associations between subject and site factors and healing of infrabony defects.
A total of 126 infrabony defects from 68 of these patients were identified at baseline and included in the analysis. Statistically significant reductions in probing pocket depth, clinical attachment loss, radiographic defect depth and a widening of the radiographic infrabony defect angle were detected following treatment. Initial defect depth and use of adjunctive antibiotics were positively associated with a reduction of radiographic defect depth, whereas smoking showed a negative association.
Within the limitations of a retrospective analysis with no control group, this study shows favourable clinical and radiographic outcomes in periodontal infrabony defects following non-surgical therapy, with complete bone fill in some cases.
本回顾性研究旨在分析非手术治疗后龈下缺损的临床和影像学反应，并检测与这种反应相关的因素。
从接受非手术牙周治疗的 143 例连续患者中获取临床和影像学数据，并由同一位临床医生重新评估。在基线和随访（治疗后 12-18 个月）X 光片上对龈下牙周缺损的线性放射测量。进行多水平分析以分析受试者和部位因素与龈下缺损愈合之间的关联。
在这些患者中的 68 名患者中，共确定了 126 个基线龈下缺损，并纳入了分析。治疗后，探诊袋深度、临床附着丧失、放射状缺损深度和放射状龈下缺损角度的扩大均有统计学显著减少。初始缺损深度和使用辅助抗生素与放射状缺损深度的减少呈正相关，而吸烟则呈负相关。
在没有对照组的回顾性分析的限制下，本研究显示非手术治疗后牙周龈下缺损具有良好的临床和影像学结果，在某些情况下可完全骨填充。
