Ju Weizhu, Yang Bing, Chen Hongwu, Zhang Fengxiang, Zhai Lishang, Cao Kejiang, Chen Minglong
Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Pacing Clin Electrophysiol. 2011 Apr;34(4):391-7. doi: 10.1111/j.1540-8159.2010.02970.x. Epub 2010 Nov 22.
Atrial tachycardia (AT) is commonly encountered after atrial fibrillation (AF) ablation. But no study exclusively on noncavotricuspid isthmus-dependent right AT (NCTI-RAT) post-AF ablation has been reported. The present study aims to describe its prevalence, electrophysiological mechanisms, and ablation strategy and to further discuss its relationship with AF.
From July 2006 to November 2009, 350 consecutive patients underwent catheter ablation for paroxysmal AF. A total of seven patients (2.0%) developed NCTI-RAT after left atrium ablation for AF. In these highly selected patients (two male, mean age 54 ± 11 years, mean left atrium diameter of 34 ± 7 cm), all had circumferential pulmonary vein isolation in their initial procedures and three of them had additional complex fractionated electrograms ablation in the left atrium and the coronary sinus.
Totally, nine NCTI-RATs were mapped and successfully ablated in the right atrium with a mean cycle length of 273 ± 64 ms in seven patients. Five ATs in three patients were electrophysiologically proved to be macroreentry and the remaining four were focal activation. All the ATs were successfully abolished by catheter ablation. After a mean follow-up of 29 ± 15 months post-AT ablation, all patients were free of AT and AF off antiarrhythmic drugs.
NCTI-RAT is relatively less common post-AF ablation. Totally, 2.0% of paroxysmal AF patients were revealed to have NCTI-RAT.
房性心动过速(AT)在房颤(AF)消融术后较为常见。但尚无专门针对房颤消融术后非三尖瓣峡部依赖性右房性心动过速(NCTI-RAT)的研究报道。本研究旨在描述其发生率、电生理机制及消融策略,并进一步探讨其与房颤的关系。
2006年7月至2009年11月,350例连续性患者接受了阵发性房颤导管消融术。共有7例患者(2.0%)在房颤左房消融术后发生NCTI-RAT。在这些经过严格筛选的患者中(2例男性,平均年龄54±11岁,平均左房直径34±7cm),所有患者在初始手术中均进行了环肺静脉隔离,其中3例患者在左房和冠状窦进行了额外的碎裂电位消融。
共对7例患者右房内的9次NCTI-RAT进行了标测并成功消融,平均周长为273±64ms。3例患者中的5次房性心动过速经电生理证实为大折返,其余4次为局灶性激动。所有房性心动过速均通过导管消融成功消除。在房性心动过速消融术后平均随访29±15个月,所有患者在停用抗心律失常药物后均未再发房性心动过速和房颤。
NCTI-RAT在房颤消融术后相对少见。阵发性房颤患者中共有2.0%被发现患有NCTI-RAT。