Cardiology Division, the First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.
J Interv Card Electrophysiol. 2023 Oct;66(7):1641-1650. doi: 10.1007/s10840-023-01482-3. Epub 2023 Jan 24.
This study aims to evaluate the prevalence, clinical characteristics, electrophysiological mechanisms, and long-term outcomes of right atrial tachycardia (AT) in patients who underwent ablation for atrial fibrillation (AF).
From March 2010 to December 2020, 220 consecutive patients undergoing index AF ablation were referred for post-ablation AT recurrence. Thirty-five patients (35/220, 15.9%) with right AT recurrence (25 men; mean age 59.3 ± 10.2 years) were enrolled. These patients were divided into groups with right ATs exclusively (group 1) and right combined with left ATs (group 2).
Fifty-three ATs were mapped in all patients, with thirty-nine ATs originating from the right atrium. The detailed distribution of all right ATs was 22 in the cavo-tricuspid isthmus (CTI), 6 in the ostium of superior vein cava (SVC), 4 in the right free wall, 4 in the right anterior atrial septum, 2 in coronary sinus ostium, and 1 in crista terminalis. Group 2 had a significantly higher incidence of typical atrial flutter (AFL) than group 1 (11/12, 90.9% vs. 12/24, 50.0%, P = 0.03). During the mean follow-up of 43.6 ± 25.2 months after the index AT ablation, the recurrence rate of AT/AF was 22.9% (8/35), and it was lower in group 1 than in group 2 (8.3% vs. 54.5%, P = 0.01).
Right AT is relatively less common post-AF ablation. The CTI-dependent AFL and the ostium of SVC-derived focal AT constituted the major components of right ATs, suggesting the importance of ablation- and anatomy-related arrhythmogenic effects in the right atrium.
本研究旨在评估接受房颤(AF)消融治疗的患者中右房心动过速(AT)的发生率、临床特征、电生理机制和长期预后。
2010 年 3 月至 2020 年 12 月,220 例连续接受指数 AF 消融的患者因消融后 AT 复发而转介。35 例(220 例中的 35 例,15.9%)出现右房 AT 复发(25 例男性;平均年龄 59.3±10.2 岁)的患者被纳入研究。这些患者分为右房 AT 组(组 1)和右房合并左房 AT 组(组 2)。
所有患者共标测到 53 次 AT,其中 39 次起源于右心房。所有右房 AT 的详细分布为 22 次位于腔静脉峡部(CTI),6 次位于上腔静脉口(SVC),4 次位于右房游离壁,4 次位于右房前房间隔,2 次位于冠状窦口,1 次位于心耳终嵴。组 2 中典型房扑(AFL)的发生率明显高于组 1(11/12,90.9% vs. 12/24,50.0%,P=0.03)。在指数 AT 消融后平均 43.6±25.2 个月的随访中,AT/AF 的复发率为 22.9%(8/35),组 1 低于组 2(8.3% vs. 54.5%,P=0.01)。
AF 消融后右房 AT 相对较少见。CTI 依赖性 AFL 和 SVC 口起源的局灶性 AT 构成了右房 AT 的主要成分,提示右房消融和解剖相关的心律失常效应的重要性。