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活力预测了在心境、焦虑和躯体形式障碍的常规治疗中遵循指南的护理水平。

Vitality predicts level of guideline-concordant care in routine treatment of mood, anxiety and somatoform disorders.

机构信息

Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.

出版信息

J Eval Clin Pract. 2012 Apr;18(2):441-8. doi: 10.1111/j.1365-2753.2010.01593.x. Epub 2010 Nov 22.

Abstract

OBJECTIVE

To examine the clinical and psychosocial correlates of adherence to treatment guidelines among outpatients with common mental disorders in a routine clinical setting.

METHODS

In this retrospective cohort study, we analysed 192 patients who were treated for a mood, anxiety or somatoform disorder with pharmacotherapy, psychotherapy or a combination of both treatment modalities. Guideline adherence was assessed with a disorder independent set of quality indicators during up to 3 years of follow-up. At baseline, a standardized diagnostic interview, the Brief Symptom Inventory (BSI), the Short Form 36 (SF-36) and demographic variables were assessed. Using multivariable regression analysis we identified independent predictors associated with guideline adherence.

RESULTS

Patients were aged 36.8 years (SD 11.6) on average. The majority of patients were treated with psychotherapy (47.4%), followed by pharmacotherapy (37.5%) and a combination of pharmacotherapy and psychotherapy (15.1%). Three adherence groups were defined: low (29.7%), intermediate (43.2%) and high (27.1%). Univariate predictors of low adherence were low scores on the subscales vitality and social functioning of the SF-36. In the multivariable model, low adherence was independently predicted by a score lower than 50 on the subscale vitality of the SF-36 (odds ratio per 10 units increase in vitality = 1.34, 95% confidence interval: 1.06-1.71). No significant differences were found within socio-demographic variables, co-morbidity and the scores on the BSI subscales between the adherence groups.

CONCLUSIONS

We found that patients with low scores on the vitality subscale of the SF-36 were at the highest risk to receive low guideline-concordant care. Understanding factors that affect treatment adherence may help to prevent non-adherence and increase the quality of care as well as cost-effectiveness.

摘要

目的

在常规临床环境中,研究门诊常见精神障碍患者治疗指南依从性的临床和心理社会学相关性。

方法

在这项回顾性队列研究中,我们分析了 192 名接受药物治疗、心理治疗或两者联合治疗的心境、焦虑或躯体形式障碍患者。在长达 3 年的随访期间,使用独立于疾病的一组质量指标评估指南依从性。在基线时,评估了标准化诊断访谈、简明症状量表(BSI)、简短健康量表(SF-36)和人口统计学变量。使用多变量回归分析确定与指南依从性相关的独立预测因素。

结果

患者的平均年龄为 36.8 岁(SD 11.6)。大多数患者接受心理治疗(47.4%),其次是药物治疗(37.5%)和药物联合心理治疗(15.1%)。定义了三个依从性组:低(29.7%)、中(43.2%)和高(27.1%)。低依从性的单变量预测因素是 SF-36 活力和社会功能子量表得分低。在多变量模型中,SF-36 活力子量表得分低于 50 分与低依从性独立相关(活力每增加 10 个单位,优势比为 1.34,95%置信区间:1.06-1.71)。在依从性组之间,社会人口统计学变量、合并症和 BSI 子量表得分没有显著差异。

结论

我们发现 SF-36 活力子量表得分低的患者接受低指南一致护理的风险最高。了解影响治疗依从性的因素可能有助于预防不依从,提高护理质量和成本效益。

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