Princess Margaret Hospital, Christchurch, New Zealand.
Int Psychogeriatr. 2011 Apr;23(3):503-4. doi: 10.1017/S1041610210002206. Epub 2010 Nov 24.
There is considerable evidence that pro-cholinergic agents can cause depressed mood. However, there are also published case reports of a rare association between cholinesterase inhibitors and mood elevation in patients with pre-existing major functional psychiatric disorders, or organic disorders other than dementia. This report adds to the literature by describing a case of mood elevation in a patient without pre-existing psychiatric disorder.
有大量证据表明拟胆硷能药物可引起情绪低落。然而,也有文献报道过在伴有先前存在的主要功能性精神疾病或除痴呆以外的器质性疾病的患者中,胆碱酯酶抑制剂与情绪升高之间罕见的关联。本报告通过描述一例无先前精神疾病的患者情绪升高的病例,为文献增添了新内容。