局限性肺切除术治疗周围型小肺癌。
Limited pulmonary resection for peripheral small-sized adenocarcinoma of the lung.
机构信息
Second Department of Surgery, University of Occupational and Environmental Health, School of Medicine, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
出版信息
Int J Surg. 2011;9(2):155-9. doi: 10.1016/j.ijsu.2010.10.011. Epub 2010 Nov 18.
BACKGROUND
It was recently reported that a limited pulmonary resection (segmentectomy or wedge resection) was not inferior to a lobectomy in the management of peripheral small-sized adenocarcinoma (tumor ≦ 20 mm) of the lung.
METHODS
We retrospectively analyzed patients undergoing a lobectomy (n = 114) and a limited resection (n = 35) for peripheral small-sized adenocarcinoma of the lung during a 7-year period from April 2001 to March 2008. Our criteria for the limited resection of lung cancer were as follows: (1) adenocarcinoma of 10 mm or less in diameter and (2) adenocarcinoma of 11-20 mm in diameter, in which the ratio of the ground glass opacity is 50% or more, without pleural indentation on computed tomography. Additionally, the frozen sections of the tumors were intraoperatively diagnosed as Noguchi type A or B. The survival and clinical outcomes were analyzed.
RESULTS
The 5-year survival rates of the lobectomy group and limited resection groups were 89.2% and 100%, respectively. No recurrence was seen in the limited resection group.
CONCLUSIONS
Our results suggest that our criteria for limited resection were adequate for the management of small-sized adenocarcinoma of the lung.
背景
最近有报道称，对于肺外周小型（肿瘤 ≦ 20mm）的小细胞肺癌，局限性肺切除术（节段切除术或楔形切除术）并不逊于肺叶切除术。
方法
我们回顾性分析了 2001 年 4 月至 2008 年 3 月期间，7 年间接受肺叶切除术（n=114）和局限性切除术（n=35）的肺外周小细胞腺癌患者的临床资料。我们对肺癌局限性切除术的标准如下：（1）直径≦10mm 的腺癌；（2）直径为 11-20mm 的腺癌，其中磨玻璃密度的比例为 50%或以上，计算机断层扫描未见胸膜凹陷。此外，肿瘤的冷冻切片术中被诊断为野口 A 型或 B 型。分析了患者的生存和临床结局。
结果
肺叶切除术组和局限性切除术组的 5 年生存率分别为 89.2%和 100%。局限性切除术组未见复发。
结论
我们的结果表明，我们对局限性切除术的标准适用于肺外周小细胞肺癌的治疗。
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