Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA.
Pediatr Neurol. 2010 Dec;43(6):427-30. doi: 10.1016/j.pediatrneurol.2010.06.009.
Electroconvulsive therapy was successfully used to treat malignant catatonia in a 15-year-old male patient with congenital dysgenesis of the left hemisphere of the cerebellum and hypoplasia of the vermis and left pons due to a presumed cerebral vascular accident in utero. The patient experienced significant motor and communication delays with mild cognitive impairment, but was otherwise in good health until age 15 years, when he developed rigidity, posturing, stupor, unresponsiveness, repetitive self-injurious behaviors, and negativism, as well as autonomic abnormalities including profuse diaphoresis and flushing episodes, thus meeting criteria for malignant catatonia. After initial response to lorazepam, the patient required electroconvulsive therapy for resolution of malignant catatonia. The case supports the safe and efficacious usage of electroconvulsive therapy for catatonia in adolescents with cerebellar and other developmental disorders. The role of the cerebellum in catatonia is also reviewed.
电抽搐治疗成功地用于治疗一名 15 岁男性患者的恶性紧张症，该患者由于宫内 presumed 脑血管意外导致左侧小脑半球先天性发育不良和蚓部及左侧脑桥发育不良。患者存在明显的运动和沟通延迟以及轻度认知障碍，但除此之外身体健康，直到 15 岁时，他出现了僵直、姿势异常、昏迷、无反应、反复的自我伤害行为和消极态度，以及自主神经异常，包括多汗和潮红发作，从而符合恶性紧张症的标准。在最初对劳拉西泮有反应后，该患者需要电抽搐治疗来缓解恶性紧张症。该病例支持在青少年中使用电抽搐治疗小脑和其他发育障碍相关的紧张症的安全性和有效性。还回顾了小脑在紧张症中的作用。
