Division of Pediatric Neurology, Department of Neurology, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, Indiana 46202, USA.
Pediatr Neurol. 2010 Dec;43(6):435-8. doi: 10.1016/j.pediatrneurol.2010.06.010.
A previously healthy 14-year-old boy collapsed after a football game, with aphasia and right hemiparesis. Cranial magnetic resonance imaging and magnetic resonance angiography revealed left middle cerebral artery distribution ischemic infarct with thrombus and possible dissection at the horizontal segment of the middle cerebral artery. The patient was treated 9 hours after collapse with intra-arterial tissue plasminogen activator, but without success. The Merci clot retrieval device was then used, but the device broke in the middle cerebral artery and led to complete occlusion. At follow-up 3 months later, the boy had persistent aphasia, but notable improvement in his right hemiparesis. This is a novel report of a complication of mechanical clot retrieval treatment in a child. Further research is needed to determine the safety and effectiveness of intracranial endovascular clot retrieval devices in children.
一名既往健康的 14 岁男孩在一场足球赛后突然倒地,出现言语障碍和右侧偏瘫。头颅磁共振成像和磁共振血管造影显示左侧大脑中动脉分布区域的缺血性梗死,伴有血栓形成,可能在大脑中动脉水平段发生夹层。患者在发病后 9 小时接受了动脉内组织型纤溶酶原激活物治疗,但未成功。随后使用了 Merci 血栓取出装置,但该装置在大脑中动脉中段断裂,导致完全闭塞。3 个月后随访时,患儿仍存在持续性言语障碍,但右侧偏瘫明显改善。这是一例儿童机械性血栓取出治疗并发症的新报告。需要进一步研究以确定颅内血管内血栓取出装置在儿童中的安全性和有效性。