Division of Pediatric Immunology, Allergy, and Rheumatology, Department of Pediatrics, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
Pediatr Neurol. 2010 Dec;43(6):442-4. doi: 10.1016/j.pediatrneurol.2010.06.020.
Aspergillus is a frequently observed pathogen in patients with chronic granulomatous disease. We report on a patient with chronic granulomatous disease and severe brain aspergillosis with an unusual presentation and favorable course. We discuss the impact of this infection on morbidity and mortality, adequate therapeutic management, and the need to investigate a possible fungal infection, despite nonspecific signs.
曲霉菌是慢性肉芽肿病患者中经常观察到的病原体。我们报告了一例患有慢性肉芽肿病和严重脑曲霉病的患者，其表现不典型但预后良好。我们讨论了这种感染对发病率和死亡率的影响，适当的治疗管理，以及即使没有特异性体征，也需要调查是否存在真菌感染的必要性。
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