Khlebnikov Rostislav, Muehl Judith
Institute for Computer Graphics and Vision, Graz University of Technology, Inffeldgasse 16, A-8010, Austria.
Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:716-21. doi: 10.1109/IEMBS.2010.5626103.
The correct needle placement is one of the crucial tasks in performing radiofrequency tumor ablation (RFA). In this work we evaluated the effects of imperfect needle placement for RFAs that are performed with an expandable needle array by using a finite-element simulation. We performed simulations for normal liver tissue with hypo- and hyperperfused metastasis as well as for cirrhotic liver tissue with hepatocellular carcinoma (HCC). We found that the shortest distance from tumor to the border of the ablated region is significantly smaller even for just 5mm deviation from the position recommended by the generator manufacturer. In case of hyperperfused metastasis even the tumor itself might stay unablated which means a very high probability of local tumor recurrence. These results provide valuable information on acceptability of inaccurate needle position to the radiologist performing RFA.
正确的针放置是进行射频肿瘤消融（RFA）的关键任务之一。在这项工作中，我们通过有限元模拟评估了使用可扩张针阵列进行RFA时针放置不完美的影响。我们对具有低灌注和高灌注转移的正常肝组织以及患有肝细胞癌（HCC）的肝硬化肝组织进行了模拟。我们发现，即使与发生器制造商推荐的位置仅偏差5mm，肿瘤到消融区域边界的最短距离也会显著变小。在高灌注转移的情况下，甚至肿瘤本身可能仍未被消融，这意味着局部肿瘤复发的可能性非常高。这些结果为进行RFA的放射科医生提供了关于针位置不准确的可接受性的有价值信息。
