Sánchez Peña R S, Ghersin A S
Centro de Sistemas y Control, Department of Physics & Mathematics Buenos Aires Institute of Technology (ITBA), Argentina.
Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:680-3. doi: 10.1109/IEMBS.2010.5626217.
This paper considers the problem of automatically controlling the glucose level in a Diabetes type I patient. Three issues have been considered: model uncertainty, time-varying/nonlinear phenomena and controller implementation. To that end, the dynamical model of the insulin/glucose relation is framed as a Linear Parameter Varying system and a controller is designed based on it. In addition, this framework allows not only a better performance than other classical methods, but also provides stability and performance guarantees. Design computations are based on convex Linear Matrix Inequality (LMI) optimization. Implementation is based on a low order controller whose dynamics adapts according to the glucose levels measured in real-time.