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低强度电磁辐射调节酶活性的研究综述。

Review of studies on modulating enzyme activity by low intensity electromagnetic radiation.

作者信息

Vojisavljevic Vuk, Pirogova Elena, Cosic Irena

机构信息

School of Electrical and Computer Engineering, RMIT University, GPO Box 2476 Melbourne 3001 Victoria Australia.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:835-8. doi: 10.1109/IEMBS.2010.5626786.

Abstract

This paper is a compilation of our findings on non-thermal effects of electromagnetic radiation (EMR) at the molecular level. The outcomes of our studies revealed that that enzymes' activity can be modulated by external electromagnetic fields (EMFs) of selected frequencies. Here, we discuss the possibility of modulating protein activity using visible and infrared light based on the concepts of protein activation outlined in the resonant recognition model (RRM), and by low intensity microwaves. The theoretical basis behind the RRM model expounds a potential interaction mechanism between electromagnetic radiation and proteins as well as protein-protein interactions. Possibility of modulating protein activity by external EMR is experimentally validated by irradiation of the L-lactate Dehydrogenase enzyme.

摘要

本文是我们在分子水平上关于电磁辐射(EMR)非热效应研究结果的汇编。我们的研究结果表明,特定频率的外部电磁场(EMF)可以调节酶的活性。在此,我们基于共振识别模型(RRM)中概述的蛋白质激活概念,以及低强度微波,讨论使用可见光和红外光调节蛋白质活性的可能性。RRM模型背后的理论基础阐述了电磁辐射与蛋白质之间以及蛋白质 - 蛋白质相互作用的潜在相互作用机制。通过对L - 乳酸脱氢酶进行辐照,实验验证了外部EMR调节蛋白质活性的可能性。

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