Chang David C, Dokos Socrates, Lovell Nigel H
Graduate School of Biomedical Engineering, University of New South Wales, Sydney, 2052 Australia.
Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:1481-4. doi: 10.1109/IEMBS.2010.5626847.
The Modeling Markup Language (MML) framework is a conceptual paradigm to quickly develop and solve biological models utilizing the CellML specification. In this study, we present the open source toolkit developed for this project and a possible workflow to create different scales of cardiac tissue models from a range of CellML models. Models from the CellML repository and other sources were tested for interoperability against the MML framework. Furthermore, to demonstrate the ability of the MML framework to deploy different scales of geometry, a model of atrial electrical activation is also presented.
建模标记语言（MML）框架是一种概念范式，用于利用CellML规范快速开发和求解生物模型。在本研究中，我们展示了为该项目开发的开源工具包以及从一系列CellML模型创建不同尺度心脏组织模型的可能工作流程。对来自CellML存储库和其他来源的模型进行了针对MML框架的互操作性测试。此外，为了证明MML框架部署不同尺度几何形状的能力，还展示了一个心房电激活模型。
