Guillem Maria S, Climent Andreu M, Millet Jose, Berne Paola, Ramos Rafael, Brugada Josep, Brugada Ramon
BIO-ITACA at Universidad Politécnica de Valencia, 46022, Spain.
Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:2537-40. doi: 10.1109/IEMBS.2010.5626869.
Brugada syndrome (BrS) causes sudden death in patients with structurally normal hearts. Manifestation of BrS in the ECG is dynamical and most patients do not show unequivocal signs of the syndrome during ECG screening. We have obtained 67-lead body surface potential mapping recordings of 25 patients with BrS and analyzed their spatial distribution of surface potentials during ventricular activation. Six patients presented spontaneous type I ECGs during the recording. These patients showed non-dipolarities in isopotential maps at the right ventricular outflow tract (RVOT) region during the development of terminal R waves in right precordial leads. Same finding was observed in 95% of BrS patients not presenting a type I ECG. Conduction delay in the RVOT may be a consistent finding in BrS patients that can be identified by Body Surface Potential Mapping.
Brugada综合征（BrS）可导致心脏结构正常的患者猝死。BrS在心电图中的表现是动态的，大多数患者在心电图筛查期间未表现出该综合征的确切迹象。我们获取了25例BrS患者的67导联体表电位标测记录，并分析了心室激动期间其表面电位的空间分布。6例患者在记录过程中出现自发性I型心电图。这些患者在右胸前导联终末R波形成过程中，右心室流出道（RVOT）区域的等电位图显示出非偶极现象。在95%未出现I型心电图的BrS患者中也观察到了相同的结果。RVOT传导延迟可能是BrS患者的一个一致表现，可通过体表电位标测来识别。
