Elias de Oliveira Marcelo, Hallila Harri, Ritvanen Antti, Büchler Philippe, Paulasto Mervi, Hukki Jyri
Institut for Surgical Technology and Biomechanics, University of Bern, Stauffacherstr. 78, CH-3014, Switzerland.
Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:5620-3. doi: 10.1109/IEMBS.2010.5626798.
Craniosynostosis consists of a premature fusion of the sutures in an infant skull, which restricts the skull and brain growth. During the last decades there has been a rapid increase of fundamentally diverse surgical treatment methods. At present, the surgical outcome has been assessed using global variables such as cephalic index, head circumerence and intracranial volume. However, the variables have failed in describing the local deformations and morphological changes, which are proposed to more likely induce neurological disorders.
颅缝早闭是指婴儿颅骨缝线过早融合，从而限制颅骨和大脑的生长。在过去几十年里，从根本上不同的手术治疗方法迅速增加。目前，手术结果是使用诸如头指数、头围和颅内体积等整体变量来评估的。然而，这些变量未能描述局部变形和形态变化，而这些变化更有可能诱发神经疾病。
