Rag4葡萄糖传感器参与了乳酸克鲁维酵母中KlPDC1基因表达的缺氧诱导过程。
The Rag4 glucose sensor is involved in the hypoxic induction of KlPDC1 gene expression in the yeast Kluyveromyces lactis.
作者信息
Micolonghi C, Wésolowski-Louvel M, Bianchi M M
机构信息
Dipartimento di Biologia e Biotecnologie Charles Darwin, Sapienza Università di Roma, 00185 Rome, Italy.
出版信息
Eukaryot Cell. 2011 Jan;10(1):146-8. doi: 10.1128/EC.00251-10. Epub 2010 Nov 19.
Abstract
Kluyveromyces lactis is a yeast which cannot grow under strict anaerobiosis. To date, no factors responsible for oxygen sensing and oxygen-dependent regulation of metabolism have been identified. In this paper we present the identification of the glucose sensor Rag4 as a factor essential for oxygen-dependent regulation of the fermentative pathway.
摘要
乳酸克鲁维酵母是一种在严格厌氧条件下无法生长的酵母。迄今为止，尚未发现负责氧气感知和代谢的氧依赖性调节的因素。在本文中，我们展示了葡萄糖传感器Rag4的鉴定，它是发酵途径氧依赖性调节所必需的一个因素。
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