Ye Ziyin, Shi Huijuan, Peng Tingsheng, Han Anjia
Department of Pathology, The First Affiliated Hospital and Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, China.
Interact Cardiovasc Thorac Surg. 2011 Jan;12(1):94-5. doi: 10.1510/icvts.2010.249300. Epub 2010 Oct 22.
Primary cardiac sarcomas are very rare. We report one case of primary cardiac osteosarcoma arising from the left atrium of a 42-year-old woman and analyze its clinical and pathological features. Histopathologic examination revealed the tumor was composed of massive osteoid and cartilaginous differentiation embedded in spindle and polygonal cells with marked cytological and nuclear pleomorphism. The patient was alive without recurrence or metastasis at 20 months after surgery without further adjuvant chemotherapy or radiotherapy.
原发性心脏肉瘤非常罕见。我们报告一例起源于一名42岁女性左心房的原发性心脏骨肉瘤，并分析其临床和病理特征。组织病理学检查显示，肿瘤由大量类骨质和软骨分化组成，包埋于梭形和多角形细胞中，具有明显的细胞和核多形性。该患者术后20个月存活，未进行进一步的辅助化疗或放疗，无复发或转移。
