Bioinformatics and Genomics Department, Centro de Investigaciones Príncipe Felipe, Valencia, Spain.
Bioinformatics. 2011 Jan 1;27(1):137-9. doi: 10.1093/bioinformatics/btq594. Epub 2010 Nov 23.
The development of the omics technologies such as transcriptomics, proteomics and metabolomics has made possible the realization of systems biology studies where biological systems are interrogated at different levels of biochemical activity (gene expression, protein activity and/or metabolite concentration). An effective approach to the analysis of these complex datasets is the joined visualization of the disparate biomolecular data on the framework of known biological pathways.
We have developed the Paintomics web server as an easy-to-use bioinformatics resource that facilitates the integrated visual analysis of experiments where transcriptomics and metabolomics data have been measured on different conditions for the same samples. Basically, Paintomics takes complete transcriptomics and metabolomics datasets, together with lists of significant gene or metabolite changes, and paints this information on KEGG pathway maps.
Paintomics is freely available at http://www.paintomics.org.
转录组学、蛋白质组学和代谢组学等组学技术的发展使得系统生物学研究成为可能，在系统生物学研究中，可以在不同的生化活性水平（基因表达、蛋白质活性和/或代谢物浓度）上研究生物系统。分析这些复杂数据集的一种有效方法是在已知生物途径的框架上联合可视化不同的生物分子数据。
我们开发了 Paintomics 网络服务器，它是一个易于使用的生物信息学资源，便于对同一样本在不同条件下测量的转录组学和代谢组学数据进行集成可视化分析。基本上，Paintomics 采用完整的转录组学和代谢组学数据集，以及显著的基因或代谢物变化列表，并将这些信息绘制在 KEGG 途径图谱上。
Paintomics 可免费在 http://www.paintomics.org 获得。
