Badr E E, Kandeel E M, El-Sadek B M
Chemistry Department, Faculty of science, Al-Azhar University (Girls), Egypt.
J Oleo Sci. 2010;59(12):647-52. doi: 10.5650/jos.59.647.
A fatty hydrazide based cationic gemini surfactants, 1,3-bis (N'-acyl-N,N-dimethylhydrazinium) propane dibromide which possess hydrolyzable amido moieties in the lipophilic portions, were prepared by reacting 1,3-bromopropane with N,N-dimethyl fatty hydrazide. The surface properties were explained and discussed based on the effect of their chemical structures. The micelle-forming ability, foaming ability, and foam stability were evaluated. The prepared surfactants also showed some antimicrobial activity against gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus) but they were not active against gram negative bacteria (Escherichia coli, P. aeruginosa), yeast (Candida albicans), and molds (Aspergillus niger).
一种基于脂肪酰肼的阳离子双子表面活性剂，1,3-双（N'-酰基-N,N-二甲基肼鎓）丙烷二溴化物，其亲脂部分含有可水解的酰胺基团，是通过1,3-溴丙烷与N,N-二甲基脂肪酰肼反应制备的。基于其化学结构的影响对表面性质进行了解释和讨论。评估了其形成胶束的能力、发泡能力和泡沫稳定性。所制备的表面活性剂对革兰氏阳性菌（枯草芽孢杆菌、金黄色葡萄球菌）也表现出一定的抗菌活性，但对革兰氏阴性菌（大肠杆菌、铜绿假单胞菌）、酵母（白色念珠菌）和霉菌（黑曲霉）无活性。
