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胰岛移植供体中伴有门周胰腺的部分背侧发育不全。

Partial dorsal agenesis accompanied with circumportal pancreas in a donor for islet transplantation.

机构信息

Clinical Islet Laboratory and Clinical Islet Transplant Program, University of Alberta, Alberta Canada.

出版信息

Islets. 2010 May-Jun;2(3):146-8. doi: 10.4161/isl.2.3.11715.

Abstract

As embryonic development of the pancreas progresses, a wide range of congenital anomalies and variations can occur. We report on the incidental observation of partial agenesis of the dorsal pancreas coexistent with cricumportal pancreas in a donor for islet transplantation. We successfully recovered a high yield of islets from such a pancreas, and the islet recipient achieved insulin independence after transplant. This case report discusses the suitability of the anomalous pancreas as a donor organ for islet transplant and the possible embryologic association between the two entities.

摘要

随着胰腺胚胎发育的进行,可能会发生广泛的先天性异常和变异。我们报告了一例胰岛移植供体中偶然观察到的背侧胰腺部分发育不全伴门腔周围胰腺的病例。我们成功地从这样的胰腺中回收了高产量的胰岛,胰岛受者在移植后实现了胰岛素独立性。本病例报告讨论了这种异常胰腺作为胰岛移植供体器官的适宜性,以及这两个实体之间可能的胚胎学关联。

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