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老年人迟发性阿尔茨海默病。

Late onset Alzheimer's disease in older people.

机构信息

Department of Internal Medicine, Division of Geriatric Medicine, Gulhane School of Medicine, Ankara, Turkey.

出版信息

Clin Interv Aging. 2010 Oct 11;5:307-11. doi: 10.2147/CIA.S11718.

Abstract

Dementia has become a common diagnosis in aging populations, and the numbers will increase in the forthcoming years. Alzheimer's disease (AD) is the most common form of dementia in the elderly, accounting for 50%-56% of cases at autopsy and in clinical series. Nowadays, the number of people affected by AD is rapidly increasing, and more than 35 million people worldwide have AD, a condition characterized by deterioration of memory and other cognitive domains, and leading to death 3-9 years after diagnosis. The number of patients with AD, the most common cause of disability in the elderly, is set to rise dramatically. Therefore, it is important for clinicians to recognize early signs and symptoms of dementia and to note potentially modifiable risk factors and early disease markers.

摘要

痴呆症在老龄化人口中已成为常见诊断,且在未来几年内其数量还将增加。阿尔茨海默病(AD)是老年人中最常见的痴呆形式,尸检和临床系列中占 50%-56%。如今,受 AD 影响的人数正在迅速增加,全世界有超过 3500 万人患有 AD,这种疾病的特征是记忆和其他认知领域的恶化,并导致诊断后 3-9 年内死亡。AD 患者数量,即老年人中最常见的致残原因,预计将大幅上升。因此,临床医生识别痴呆的早期迹象和症状,并注意潜在可改变的风险因素和早期疾病标志物非常重要。

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