Rocha Paulo Novis, de Menezes Jorge Arnaldo Valente, Suassuna José Hermógenes Rocco
Medicine Department of Faculdade de Medicina da Bahia – Universidade Federal da Bahia, Salvador – BA – Brazil.
J Bras Nefrol. 2010 Apr-Jun;32(2):201-12.
A growing fraction of the clinical duties of Nephrologists is undertaken inside intensive care units. While assessing patients with acute renal failure in the context of circulatory collapse, which are also edematous and/or with impaired gas exchanges, the Nephrologist must decide between two opposing therapies: 1) remove volume with the aid of dialysis or diuretics to improve the edematous state; 2) volume expand to improve hemodynamics. To minimize the odds of making incorrect choices, the Nephrologist must be familiar with the tools available for determining the adequacy of volume status and for invasive hemodynamic monitoring in the critically ill patient. In this manuscript, we will briefly review the physiology of extra cellular fluid volume regulation and then tackle the issue of volume status assessment, based on clinical and hemodynamic criteria.
肾病学家越来越多的临床工作是在重症监护病房内进行的。在评估伴有循环衰竭、水肿和/或气体交换受损的急性肾衰竭患者时,肾病学家必须在两种相反的治疗方法之间做出决定:1)借助透析或利尿剂去除液体以改善水肿状态;2)扩充液体以改善血流动力学。为了尽量减少做出错误选择的几率,肾病学家必须熟悉用于确定重症患者容量状态是否充足以及进行有创血流动力学监测的可用工具。在本手稿中,我们将简要回顾细胞外液容量调节的生理学,然后根据临床和血流动力学标准探讨容量状态评估问题。