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局部麻醉下的无症状颈动脉狭窄内膜切除术。

Endarterectomy for asymptomatic carotid artery stenosis under local anaesthesia.

机构信息

Department of Neurosurgery, Hospital Ceske Budejovice a.s., Ceske Budejovice, Czech Republic.

出版信息

Acta Neurochir (Wien). 2011 Feb;153(2):363-9. doi: 10.1007/s00701-010-0806-3. Epub 2010 Nov 23.

Abstract

BACKGROUND

In this article, we present our experience with such operations performed under local anaesthesia.

METHODS

From January 1997 to November 2007, there were 387 patients operated on for asymptomatic carotid stenosis. Patient data were retrospectively evaluated. Thirty-day neurological morbidity and mortality from six different subgroups were analysed and compared. The numbers of perioperative transient ischaemic attacks, as well as surgical and other perioperative complications were also evaluated.

RESULTS

Overall morbidity and mortality was 1.8% (seven patients). Stroke was noted in 1.3% (five patients). Transitory ischaemic attacks within the first 30 days were observed in 1.6% (six patients). Only those patients who had intraluminal shunt insertion were found to have significantly higher morbidity and mortality. (p = 0.000018). Myocardial infarction was observed in 0.5% (two patients), one fatal.

CONCLUSION

We have achieved acceptable morbidity and mortality rates (1.8%) according to the parameters set by previous studies such as Asymptomatic Carotid Atherosclerosis Study and Asymptomatic Carotid Stenosis Trial as well as American Heart Association and European Stroke Organisation guidelines. All surgeries were done under local anaesthesia. Shunts were inserted in 22 cases (5.68%).

摘要

背景

本文介绍了我们在局部麻醉下进行此类手术的经验。

方法

从 1997 年 1 月至 2007 年 11 月,共有 387 例无症状颈动脉狭窄患者接受了手术。回顾性评估患者数据。分析和比较了来自六个不同亚组的 30 天内神经功能障碍和死亡率,以及围手术期短暂性脑缺血发作的数量以及手术和其他围手术期并发症。

结果

总发病率和死亡率为 1.8%(7 例)。中风发生率为 1.3%(5 例)。在头 30 天内观察到短暂性脑缺血发作的发生率为 1.6%(6 例)。只有那些接受管内分流器插入术的患者发现发病率和死亡率明显更高。(p=0.000018)。心肌梗死发生率为 0.5%(2 例),1 例致命。

结论

我们根据以前的研究(如无症状颈动脉粥样硬化研究和无症状颈动脉狭窄试验以及美国心脏协会和欧洲中风组织指南)设定的参数,达到了可接受的发病率和死亡率(1.8%)。所有手术均在局部麻醉下进行。在 22 例(5.68%)中插入了分流器。

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