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失眠症状、睡眠药物使用与抑郁症状之间的相关性。

Correlations among insomnia symptoms, sleep medication use and depressive symptoms.

机构信息

Department of Somnology, Tokyo Medical University, Tokyo, Japan.

出版信息

Psychiatry Clin Neurosci. 2011 Feb;65(1):20-9. doi: 10.1111/j.1440-1819.2010.02154.x. Epub 2010 Nov 24.

Abstract

AIM

To elucidate the factors associated with insomnia symptoms and the use of sleep medication, and the correlations among insomnia symptoms, sleep medication use and depressive symptoms in the general population.

METHODS

This survey was conducted in a rural community of Japan. Questionnaires consisted of basic information, the Pittsburgh Sleep Quality Index, and a 12-item version of the Center for Epidemiological Studies Depression scale, and were administered to all community members aged 20 years or over. A total of 2822 respondents with valid answers were subjected to analysis.

RESULTS

Occurrence of insomnia symptoms appeared to be associated with advancing age and existence of depressive symptoms. The extent of sleep medication use in the entire sample was 9%, and the value in the subjects with insomnia symptoms was 26%. Sleep medication use in insomniacs was associated with female sex and advancing age as well as higher scores in subcomponents of both poor subjective sleep quality and prolonged delay of sleep onset. Depressive symptoms were worst in the group with insomnia symptoms using sleep medication, and were significantly lower in the group without insomnia symptoms using sleep medication.

CONCLUSIONS

Our study revealed that female sex, advancing age, depressive symptoms, poor sleep quality, and prolonged delay of sleep onset appeared as risk factors for sleep medication use. Insomnia symptoms were suspected to act as an exacerbating factor for depressive symptoms. However, our findings suggested that appropriate use of sleep medication could reduce depressive symptoms in the subjects with insomnia symptoms.

摘要

目的

阐明与失眠症状相关的因素以及睡眠药物的使用,以及失眠症状、睡眠药物使用与普通人群中抑郁症状之间的相关性。

方法

本调查在日本的一个农村社区进行。问卷包括基本信息、匹兹堡睡眠质量指数和 12 项版流行病学研究中心抑郁量表,并对所有 20 岁及以上的社区居民进行了问卷调查。共有 2822 名回答有效者接受了分析。

结果

失眠症状的发生似乎与年龄增长和抑郁症状的存在有关。整个样本中睡眠药物的使用程度为 9%,在有失眠症状的受试者中为 26%。失眠症患者的睡眠药物使用与女性、年龄增长以及主观睡眠质量差和入睡潜伏期延长的各亚组评分较高有关。在使用睡眠药物的失眠症患者中,抑郁症状最严重,而在没有失眠症状且不使用睡眠药物的患者中,抑郁症状显著降低。

结论

我们的研究表明,女性、年龄增长、抑郁症状、睡眠质量差和入睡潜伏期延长似乎是睡眠药物使用的危险因素。失眠症状可能是抑郁症状恶化的一个因素。然而,我们的研究结果表明,在有失眠症状的患者中,适当使用睡眠药物可能会减轻抑郁症状。

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