Karpov Iu A, Noeva E A, Ruda M Ia
Klin Med (Mosk). 1990 Feb;68(2):39-43.
Clinical and prognostic significance of intravenous nitroglycerin infusions (INI) were studied in 127 patients with unstable angina pectoris. INI dose ranged from 25 to 800 micrograms/min (mean 198.2 +/- 21.8 micrograms/min), the duration varied from 2 h to 20 days (mean 5.2 days). Unfavorable effects occurred in 50 patients (39.3%): 18 patients developed myocardial infarction which was fatal in 10 cases, one died of circulatory insufficiency, transluminal angioplasty was performed in 6, aortocoronary shunting in 26. INI promoted stabilization of the disease in 77 patients (60.7%). They were discharged from the hospital to continue on maintenance therapy.
对127例不稳定型心绞痛患者研究了静脉输注硝酸甘油(INI)的临床及预后意义。INI剂量范围为25至800微克/分钟(平均198.2±21.8微克/分钟),持续时间从2小时至20天不等(平均5.2天)。50例患者(39.3%)出现不良反应:18例发生心肌梗死,其中10例死亡,1例死于循环功能不全,6例行腔内血管成形术,26例行主动脉冠状动脉分流术。INI使77例患者(60.7%)病情稳定。他们出院后继续维持治疗。