Core Facility, Molecular Structure Analysis, German Cancer Research Center, Heidelberg, Germany.
Glycobiology. 2011 Apr;21(4):493-502. doi: 10.1093/glycob/cwq188. Epub 2010 Nov 23.
The EUROCarbDB project is a design study for a technical framework, which provides sophisticated, freely accessible, open-source informatics tools and databases to support glycobiology and glycomic research. EUROCarbDB is a relational database containing glycan structures, their biological context and, when available, primary and interpreted analytical data from high-performance liquid chromatography, mass spectrometry and nuclear magnetic resonance experiments. Database content can be accessed via a web-based user interface. The database is complemented by a suite of glycoinformatics tools, specifically designed to assist the elucidation and submission of glycan structure and experimental data when used in conjunction with contemporary carbohydrate research workflows. All software tools and source code are licensed under the terms of the Lesser General Public License, and publicly contributed structures and data are freely accessible. The public test version of the web interface to the EUROCarbDB can be found at http://www.ebi.ac.uk/eurocarb.
EUROCarbDB 项目是一个技术框架的设计研究,提供复杂、可自由访问、开源的信息学工具和数据库,以支持糖生物学和糖组学研究。EUROCarbDB 是一个关系数据库,包含聚糖结构、它们的生物学背景,以及从高效液相色谱、质谱和核磁共振实验中获得的原始和解释性分析数据。可以通过基于网络的用户界面访问数据库内容。该数据库由一套糖生物信息学工具补充,这些工具专门设计用于协助阐明和提交聚糖结构和实验数据,当与当代碳水化合物研究工作流程一起使用时。所有软件工具和源代码都根据较宽松的通用公共许可证条款获得许可,并且公共贡献的结构和数据可以免费访问。EUROCarbDB 的网络界面的公共测试版本可在 http://www.ebi.ac.uk/eurocarb 找到。