Al Jadda Khalifeh, Porterfield Melody P, Bridger Robert, Heiss Christian, Tiemeyer Michael, Wells Lance, Miller John A, York William S, Ranzinger Rene
Department of Computer Science and Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602, USA.
Bioinformatics. 2015 Jan 15;31(2):242-5. doi: 10.1093/bioinformatics/btu609. Epub 2014 Sep 12.
In the field of glycomics research, several different techniques are used for structure elucidation. Although multiple techniques are often used to increase confidence in structure assignments, most glycomics databases allow storing of only a single type of experimental data. In addition, the methods used to prepare a sample for analysis is seldom recorded making it harder to reproduce the analytical data and results.
We have extended the freely available EUROCarbDB framework to allow the submission of experimental data and the reporting of several orthogonal experimental datasets. The features aim to increase the understandability and reproducibility of the reported data.
The installation with the glycan standards is available at http://glycomics.ccrc.uga.edu/eurocarb/. The source code of the project is available at https://code.google.com/p/ucdb/.
Supplementary data are available at Bioinformatics online.
在糖组学研究领域,有几种不同的技术用于结构解析。尽管通常使用多种技术来提高对结构归属的可信度,但大多数糖组学数据库仅允许存储单一类型的实验数据。此外,用于制备分析样品的方法很少被记录,这使得重现分析数据和结果变得更加困难。
我们扩展了免费可用的EUROCarbDB框架,以允许提交实验数据并报告多个正交实验数据集。这些功能旨在提高所报告数据的可理解性和可重复性。
带有聚糖标准品的安装程序可在http://glycomics.ccrc.uga.edu/eurocarb/获取。该项目的源代码可在https://code.google.com/p/ucdb/获取。
补充数据可在《生物信息学》在线版获取。