Koyak Zeliha, de Groot Joris R, Mulder Barbara J M
Department of Cardiology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Expert Rev Cardiovasc Ther. 2010 Dec;8(12):1753-66. doi: 10.1586/erc.10.152.
Arrhythmias are a major cause of morbidity, mortality and hospital admission in adults with congenital heart disease (CHD). The etiology of arrhythmias in this population is often multifactorial and includes electrical disturbances as part of the underlying defect, surgical intervention or hemodynamic abnormalities. Despite the numerous existing arrhythmia management tools including drug therapy, pacing and ablation, management of arrhythmias in adults with CHD remains difficult and challenging. Owing to improvement in mapping and ablation techniques, ablation and arrhythmia surgery are being performed more frequently in adults with CHD. However, there is little information on the long-term results of these treatment strategies. The purpose of this article is therefore to review the available data on nonpharmacological treatment of cardiac arrhythmias in adult patients with CHD and to give an overview of the available data on the early and late outcomes of these treatment strategies.
心律失常是成人先天性心脏病(CHD)患者发病、死亡和住院的主要原因。该人群心律失常的病因通常是多因素的,包括作为潜在缺陷一部分的电紊乱、手术干预或血流动力学异常。尽管现有众多心律失常管理工具,包括药物治疗、起搏和消融,但成人CHD患者的心律失常管理仍然困难且具有挑战性。由于标测和消融技术的改进,CHD成人患者中消融和心律失常手术的开展越来越频繁。然而,关于这些治疗策略的长期结果的信息很少。因此,本文的目的是回顾成人CHD患者心律失常非药物治疗的现有数据,并概述这些治疗策略的早期和晚期结果的现有数据。