Schwagten Bruno, Jordaens Luc, Witsenburg Martin, Duplessis Frederik, Thornton Andrew, van Belle Yves, Szili-Torok Tamas
Department of Electrophysiology Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
Pacing Clin Electrophysiol. 2009 Mar;32 Suppl 1:S198-201. doi: 10.1111/j.1540-8159.2008.02283.x.
The improved outcomes and increased availability of surgery for congenital heart disease (CHD) over the last three decades have created a small but steadily increasing subset of patients with unique needs: children and adults with complex arrhythmias in the setting of structural cardiac abnormalities. Radiofrequency catheter ablation (RFCA) in these patients, and in small children with normal cardiac anatomy, is effective but challenging. An understanding of specific anatomical and electrophysiological characteristics of these patients and the technical challenges in addressing them are critical to the success of this therapy. Tools specifically designed for intracardiac diagnosis and therapy in anatomically complex and/or small hearts remain scarce.
We report single-center results from an ongoing registry of all patients with congenital heart disease and all children with complex arrhythmias in which the Magnetic Navigation System (MNS) was used.
Included in this report are 12 patients with CHD in whom 17 tachyarrhythmias were treated, and 11 pediatric patients with normal cardiac anatomy who each had a single arrhythmia. The procedures' duration and the duration of fluoroscopy time as well as arrhythmia recurrence rates were comparable to those found in previous reports of procedures performed in adults with structurally normal hearts, and the incidence of complications was quite low.
In patients with complex congenital malformations, retrograde mapping of the pulmonary venous atrium was feasible, eliminating the need for puncture of the atrial septum, or surgically placed baffle in many cases. Moreover, the design of the catheter eliminated the need for multiple mapping and ablation catheters.
Our findings suggest that RFCA using the MNS for arrhythmias after surgery for congenital heart disease and in pediatric patients is safe and effective.
在过去三十年中,先天性心脏病(CHD)手术效果的改善以及手术可及性的提高,造就了一小部分但数量稳步增加的有特殊需求的患者:患有结构性心脏异常并伴有复杂心律失常的儿童和成人。对这些患者以及心脏解剖结构正常的小儿患者进行射频导管消融术(RFCA)是有效的,但具有挑战性。了解这些患者的特定解剖和电生理特征以及应对这些特征的技术挑战对于该治疗的成功至关重要。专门为解剖结构复杂和/或心脏较小的患者进行心内诊断和治疗设计的工具仍然稀缺。
我们报告了一项正在进行的注册研究的单中心结果,该研究纳入了所有使用磁导航系统(MNS)的先天性心脏病患者和所有患有复杂心律失常的儿童。
本报告纳入了12例先天性心脏病患者,共治疗了17次快速性心律失常,以及11例心脏解剖结构正常的儿科患者,他们每人都有一种心律失常。手术持续时间、透视时间以及心律失常复发率与先前关于心脏结构正常的成人进行的手术报告中的结果相当,并发症发生率很低。
在患有复杂先天性畸形的患者中,肺静脉心房的逆行标测是可行的,在许多情况下无需穿刺房间隔或手术置入挡板。此外,导管的设计无需使用多个标测和消融导管。
我们的研究结果表明,使用MNS对先天性心脏病术后心律失常患者和儿科患者进行RFCA是安全有效的。