泛素信号的特异性和结果由什么决定？
What determines the specificity and outcomes of ubiquitin signaling?
机构信息
Frankfurt Institute for Molecular Life Sciences, Goethe University School of Medicine, Main, Germany.
出版信息
Cell. 2010 Nov 24;143(5):677-81. doi: 10.1016/j.cell.2010.10.026.
PMID:21111228
Abstract
Ubiquitin signals and ubiquitin-binding domains are implicated in almost every cellular process, but how is their functionality achieved in cells? We assess recent advances in monitoring the dynamics and specificity of ubiquitin networks in vivo and discuss challenges ahead.
摘要
泛素信号和泛素结合结构域几乎涉及细胞的每一个过程，但它们在细胞中是如何发挥功能的呢？我们评估了在体内监测泛素网络动态和特异性的最新进展，并讨论了未来的挑战。
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