筛选具有罕见抗原组合的献血者。
Screening Donors for Rare Antigen Constellations.
作者信息
Wagner Franz F
机构信息
DRK-Blutspendedienst NSTOB, Zentralinstitut Springe, Germany.
出版信息
Transfus Med Hemother. 2009;36(3):199-203. doi: 10.1159/000218110. Epub 2009 May 26.
Abstract
SCREENING BLOOD DONORS FOR RARE ANTIGEN CONSTELLATIONS HAS BEEN IMPLEMENTED USING SIMPLE PCR METHODS
PCR with enzyme digestion has been used to type donor cohorts for Dombrock antigens, and PCR with sequence-specific priming to identify donors negative for antigens of high frequency. The advantages and disadvantages of the methods as well as their current state is discussed.
摘要
已采用简单的聚合酶链反应（PCR）方法对献血者进行罕见抗原组合的筛查：酶切PCR已用于对献血者群体进行多姆布罗克抗原分型，序列特异性引物PCR用于识别高频抗原阴性的献血者。文中讨论了这些方法的优缺点及其当前状况。
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