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Pharmacogenetic testing to predict serious toxicity from 5-fluorouracil (5-FU) for patients administered 5-FU-based chemotherapy for cancer.

出版信息

Technol Eval Cent Assess Program Exec Summ. 2010 Aug;24(13):1-3.

PMID:21114065
Abstract
摘要

相似文献

1
Pharmacogenetic testing to predict serious toxicity from 5-fluorouracil (5-FU) for patients administered 5-FU-based chemotherapy for cancer.对接受基于5-氟尿嘧啶(5-FU)的癌症化疗的患者进行药物遗传学检测,以预测5-氟尿嘧啶的严重毒性。
Technol Eval Cent Assess Program Exec Summ. 2010 Aug;24(13):1-3.
2
[Pharmacogenetic studies on the prediction of efficacy and toxicity of fluoropyrimidine-based adjuvant therapy in colorectal cancer].[氟尿嘧啶类辅助治疗在结直肠癌中疗效及毒性预测的药物遗传学研究]
Magy Onkol. 2007;51(2):113-25. Epub 2007 Jul 29.
3
[Pharmacogenomics and chemotherapy].[药物基因组学与化疗]
Recenti Prog Med. 2010 Jul-Aug;101(7-8):277-82.
4
Implications of dihydropyrimidine dehydrogenase on 5-fluorouracil pharmacogenetics and pharmacogenomics.二氢嘧啶脱氢酶对5-氟尿嘧啶药物遗传学和药物基因组学的影响。
Pharmacogenomics. 2002 Jul;3(4):485-92. doi: 10.1517/14622416.3.4.485.
5
Dihydropyrimidine dehydrogenase and thymidylate synthase polymorphisms and their association with 5-fluorouracil/leucovorin chemotherapy in colorectal cancer.二氢嘧啶脱氢酶和胸苷酸合成酶基因多态性及其与结直肠癌5-氟尿嘧啶/亚叶酸化疗的相关性
Clin Colorectal Cancer. 2004 Feb;3(4):225-34. doi: 10.3816/CCC.2004.n.003.
6
Variants in the dihydropyrimidine dehydrogenase, methylenetetrahydrofolate reductase and thymidylate synthase genes predict early toxicity of 5-fluorouracil in colorectal cancer patients.二氢嘧啶脱氢酶、亚甲基四氢叶酸还原酶和胸苷酸合成酶基因的变异可预测结直肠癌患者中5-氟尿嘧啶的早期毒性。
J Int Med Res. 2010 May-Jun;38(3):870-83. doi: 10.1177/147323001003800313.
7
Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group.遗传和非遗传因素在氟尿嘧啶治疗相关严重毒性中的作用:德国5-氟尿嘧啶毒性研究组的一项前瞻性临床试验
J Clin Oncol. 2008 May 1;26(13):2131-8. doi: 10.1200/JCO.2006.10.4182. Epub 2008 Feb 25.
8
Prognostic value of 5-fluorouracil metabolic enzyme genes in Dukes' stage B and C colorectal cancer patients treated with oral 5-fluorouracil-based adjuvant chemotherapy.5-氟尿嘧啶代谢酶基因在接受口服5-氟尿嘧啶辅助化疗的Dukes B期和C期结直肠癌患者中的预后价值
Oncol Rep. 2008 Mar;19(3):729-35.
9
Predicting fluorouracil toxicity: can we finally do it?预测氟尿嘧啶毒性:我们最终能做到吗?
J Clin Oncol. 2008 May 1;26(13):2080-2. doi: 10.1200/JCO.2007.15.5481. Epub 2008 Feb 25.
10
Polymorphisms in the thymidylate synthase and dihydropyrimidine dehydrogenase genes predict response and toxicity to capecitabine-raltitrexed in colorectal cancer.胸苷酸合成酶和二氢嘧啶脱氢酶基因多态性可预测结直肠癌患者对卡培他滨-雷替曲塞的反应及毒性。
Oncol Rep. 2007 Feb;17(2):325-8.

引用本文的文献

1
Genotyping in Patients Who Have Planned Cancer Treatment With Fluoropyrimidines: A Health Technology Assessment.计划接受氟嘧啶类药物癌症治疗的患者的基因分型:一项卫生技术评估。
Ont Health Technol Assess Ser. 2021 Aug 12;21(14):1-186. eCollection 2021.