Stewart D W, Buffington P J, Wacksman J
Department of Surgery, University of Cincinnati College of Medicine, Ohio.
J Urol. 1990 Jun;143(6):1261-3. doi: 10.1016/s0022-5347(17)40250-3.
A comparison of polydioxanone, polyglactin, and chromic catgut suture was performed in 120 rat bladders studying propensity for infection, degree of inflammation, calculogenic potential, changes in urine pH, and suture absorption. None of the sutures predisposed to infection and there was wide variability but no correlation in urine pH. Although initially the polydioxanone incited a greater inflammatory response, by six months all three sutures were similar. The absorption of polydioxanone was slower than chromic catgut suture, but similar to the absorption of polyglactin. There was no significant difference in calculogenic potential between the suture materials tested over a six-month period. Based on this study in rats, polydioxanone suture would appear to be equal to catgut and polyglactin suture in bladder surgery.
在120只大鼠膀胱中对聚二氧六环酮、聚乙交酯丙交酯和铬制肠线缝合线进行了比较,研究感染倾向、炎症程度、结石形成潜力、尿液pH值变化和缝合线吸收情况。没有一种缝合线易引发感染,尿液pH值存在很大差异但无相关性。虽然最初聚二氧六环酮引发的炎症反应更大,但到六个月时,三种缝合线的情况相似。聚二氧六环酮的吸收比铬制肠线缝合线慢,但与聚乙交酯丙交酯的吸收相似。在六个月的测试期内,所测试的缝合线材料之间的结石形成潜力没有显著差异。基于对大鼠的这项研究,在膀胱手术中,聚二氧六环酮缝合线似乎与肠线和聚乙交酯丙交酯缝合线相当。