Sanz L E, Patterson J A, Kamath R, Willett G, Ahmed S W, Butterfield A B
Department of Obstetrics and Gynecology, Georgetown University School of Medicine, Washington, DC.
Obstet Gynecol. 1988 Mar;71(3 Pt 1):418-22.
Two hundred ten rats were randomized into one of five study groups to compare standard absorbable sutures with a new synthetic absorbable suture. We evaluated Maxon (polyglyconate), Vicryl (polyglactin), chromic catgut (catgut), and PDS (polydioxanone) with respect to tissue inflammatory reaction, knot security, suture tensile strength, and suture absorption. The results indicate that Maxon and PDS elicited a lower degree of chronic inflammation when compared with Vicryl and chromic catgut. The tensile strengths of Maxon and Vicryl significantly exceeded those of PDS and chromic catgut during the critical period of wound healing. Maxon and PDS retained a larger percentage of tensile strength during the long postoperative period, whereas Vicryl and chromic catgut were mostly absorbed. Maxon is an excellent addition to the armamentarium of the gynecologic surgeon.
210只大鼠被随机分为五个研究组之一，以比较标准可吸收缝线与一种新型合成可吸收缝线。我们评估了Maxon（聚乙醇酸酯）、Vicryl（聚乙交酯丙交酯）、铬制肠线（肠线）和PDS（聚二氧杂环己酮）在组织炎症反应、结安全性、缝线抗张强度和缝线吸收方面的情况。结果表明，与Vicryl和铬制肠线相比，Maxon和PDS引起的慢性炎症程度较低。在伤口愈合的关键时期，Maxon和Vicryl的抗张强度显著超过PDS和铬制肠线。在术后较长时期，Maxon和PDS保留了较大比例的抗张强度，而Vicryl和铬制肠线大多被吸收。Maxon是妇科外科医生器械库中的一项优秀补充。
