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腹腔镜再次袖状胃切除术与十二指肠转流术治疗单纯袖状胃切除术治疗肥胖症的对比。

Laparoscopic repeat sleeve gastrectomy versus duodenal switch after isolated sleeve gastrectomy for obesity.

机构信息

Department of Gastrointestinal Surgery, European School of Laparoscopic Surgery, Saint-Pierre University Hospital, Brussels, Belgium.

出版信息

Surg Obes Relat Dis. 2011 Jan-Feb;7(1):38-43. doi: 10.1016/j.soard.2010.08.005. Epub 2010 Aug 19.

DOI:10.1016/j.soard.2010.08.005
PMID:21115409
Abstract

BACKGROUND

Repeat sleeve gastrectomy (re-SG) and the addition of the duodenal switch (DS) are possible options to increase weight loss after isolated SG (ISG). We report the feasibility, safety, and outcomes of laparoscopic re-SG versus DS in patients presenting with insufficient weight loss or weight regain after ISG.

METHODS

From November 2003 to December 2009, 7 and 19 patients underwent laparoscopic re-SG and DS, respectively, mainly because of the patients' dietary habits: volume eating (hyperphagia) was treated by re-SG and eating meals too frequently (polyphagia) by DS.

RESULTS

At ISG, the mean weight and BMI was 127.7 ± 31.4 kg, and 45.1 ± 11.8 kg/m(2) for the re-SG group and 119.8 ± 20.9 kg and 41.2 ± 5.5 kg/m(2) for the DS group, respectively. The mean interval between ISG and reoperation was 37.1 ± 20.3 months for the re-SG group and 29.8 ± 24.9 months for the DS group. At reoperation, the mean weight, BMI, and percentage of excess weight loss (%EWL) was 109.7 ± 21 kg, 38.9 ± 8.7 kg/m(2), 24.3 ± 16.6% for the re-SG group and 107.6 ± 19.6 kg, 36.9 ± 4.2 kg/m(2), and 19.5 ± 19.9% for the DS group, respectively. The mean operative time was 137.5 ± 75.5 minutes for the re-SG group and 152.6 ± 54.3 minutes for the DS group. No conversion to open surgery was required, and no mortality occurred. One patient in the re-SG group developed a leak at the angle of His. In the DS group, 1 patient presented with bleeding, 1 patient with a duodenoileostomy leak, and 1 patient with a duodenoileostomy stenosis. The mean hospital stay was 11.5 ± 20.5 days for the re-SG group and 4.7 ± 2.7 days for the DS group. The mean follow-up was 23.2 ± 11.1 months for the re-SG group and 24.9 ± 20.1 months for the DS group. The mean weight, BMI, and %EWL was 100 ± 21.1 kg, 35.3 ± 8.3 kg/m(2), 43.7 ± 24.9% for the re-SG group and 80.7 ± 22.5 kg, 27.3 ± 5.2 kg/m(2), 73.7 ± 27.7% for the DS group, respectively. During follow-up, 3 patients in the DS group required corrective surgery for late complications.

CONCLUSION

The results of the present study have shown that laparoscopic re-SG is feasible but carries the risk of fistula development, which is difficult to treat. Laparoscopic DS was also shown to be feasible at a cost of not negligible complications, which are easier to manage than with re-SG. The efficacy seemed greater after DS than after re-SG.

摘要

背景

袖状胃切除术(re-SG)后再次进行十二指肠转位术(DS)是增加孤立性袖状胃切除术(ISG)后减重效果的可能选择。我们报告了在 ISG 后出现减重不足或体重反弹的患者中,腹腔镜下 re-SG 与 DS 的可行性、安全性和结果。

方法

从 2003 年 11 月至 2009 年 12 月,分别有 7 例和 19 例患者接受了腹腔镜下 re-SG 和 DS,主要是因为患者的饮食习惯:容积进食(贪食症)通过 re-SG 治疗,进食次数过于频繁(多食症)通过 DS 治疗。

结果

在 ISG 时,re-SG 组的平均体重和 BMI 为 127.7 ± 31.4kg 和 45.1 ± 11.8kg/m²,DS 组分别为 119.8 ± 20.9kg 和 41.2 ± 5.5kg/m²。re-SG 组和 DS 组的 ISG 与再次手术之间的平均间隔时间分别为 37.1 ± 20.3 个月和 29.8 ± 24.9 个月。在再次手术时,re-SG 组的平均体重、BMI 和超重减轻百分比(%EWL)分别为 109.7 ± 21kg、38.9 ± 8.7kg/m²、24.3 ± 16.6%,DS 组分别为 107.6 ± 19.6kg、36.9 ± 4.2kg/m²和 19.5 ± 19.9%。re-SG 组的平均手术时间为 137.5 ± 75.5 分钟,DS 组为 152.6 ± 54.3 分钟。没有转为开放手术,也没有死亡病例。re-SG 组 1 例患者出现吻合口漏,DS 组 1 例患者出现出血,1 例患者出现胆肠漏,1 例患者出现胆肠狭窄。re-SG 组的平均住院时间为 11.5 ± 20.5 天,DS 组为 4.7 ± 2.7 天。re-SG 组和 DS 组的平均随访时间分别为 23.2 ± 11.1 个月和 24.9 ± 20.1 个月。re-SG 组的平均体重、BMI 和 %EWL 分别为 100 ± 21.1kg、35.3 ± 8.3kg/m²、43.7 ± 24.9%,DS 组分别为 80.7 ± 22.5kg、27.3 ± 5.2kg/m²、73.7 ± 27.7%。在随访期间,DS 组有 3 例患者因晚期并发症需要进行矫正手术。

结论

本研究结果表明,腹腔镜下 re-SG 是可行的,但存在瘘管发展的风险,且难以治疗。腹腔镜 DS 也可行,但代价是不可忽视的并发症,其处理比 re-SG 更容易。DS 后的疗效似乎比 re-SG 后更好。

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