Prevention of enamel demineralization adjacent to glass ionomer filling materials.

In order to study the release of fluoride and prevention of enamel demineralization by different filling materials, standardized cavities were prepared in 80 extracted human molars. The cavities were filled as follows: 1. Fuji II F; 2. Ketac-Fil; 3. Ketac-Silver; 4. Silar. Twenty molars were used as controls (no filling). Enamel slabs with the fillings were subjected to 9 days of demineralization (30 min daily) and remineralization (artificial saliva, replaced daily). Fluoride release in the saliva was determined on days 1, 3, 5, and 9. Enamel fluoride content adjacent to the cavities was determined initially and after the de-remineralization using the acid etch technique. On day 1, the largest amount of fluoride in the saliva was released by Fuji, but on day 9 the largest amount was released by Ketac-Fil. Ketac-Silver released significantly less fluoride than Fuji and Ketac-Fil. The average initial fluoride content of enamel was 2200 ppm. After the test period, fluoride contents adjusted for biopsy depth were 1822, 1690, 1693, 1337, and 888 ppm in groups 1-5, respectively. The amounts of phosphorus dissolved by the second acid etch were 28.9 (SE 2.6), 30.2 (2.0), 34.4 (2.8), 44.1 (2.7), and 42.2 (2.4) micrograms, respectively. Softening of surface enamel during the test period was clearly reduced in teeth filled with Fuji and Ketac-Fil. The results show that glass ionomer materials release considerable amounts of fluoride and prevent demineralization of the adjacent enamel in vitro. Fuji and Ketac-Fil seem to be more effective than Ketac-Silver.