[The effect of alimentary hypercholesterolemia on the level of lipids and essential fatty acids in rabbit enterohepatic circulation].

Patterns of lipid metabolism were estimated in biological fluids and tissues involved in enterohepatic circulation of bile lipid complexes in female rabbits with alimentary hypercholesterolemia. Cholesterol gallstones were not found in gallbladder of rabbits with alimentary hypercholesterolemia. A number of reasons was responsible for the phenomenon, including specific ratio of four lipid components, which contributed to maintaining bile cholesterol in soluble form: concentration of bile acids was unaltered simultaneously with high contents of cholesterol and a decrease in phospholipids level, while content of free fatty acids was increased and the content of arachidonic acid was elevated in majority of lipid fractions.