司来吉兰对束缚应激期间大鼠脑内自由基氧化的影响。
Effect of deprenyl on free radical oxidation in rat brain during immobilization stress.
作者信息
Tseilikman V E, Sinitsky A I, Poyarkov K A, Vojdaev E V
机构信息
Chelyabinsk State Medical Academy, Russian Ministry of Health, Russia.
出版信息
Bull Exp Biol Med. 2009 Dec;148(6):856-8. doi: 10.1007/s10517-010-0835-1.
PMID:21116490
Abstract
Rarely repeated episodes of 1-h immobilization in rats were accompanied by an increase in the content of molecular products of lipid peroxidation and decrease in the amount of oxidatively modified proteins. Monoamine oxidase B inhibitor deprenyl prevented the poststress activation of lipid peroxidation.
摘要
大鼠中很少重复出现的1小时固定不动期，伴随着脂质过氧化分子产物含量的增加以及氧化修饰蛋白质数量的减少。单胺氧化酶B抑制剂司来吉兰可防止应激后脂质过氧化的激活。
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