Bourmayan C, Desnos M, Baragan J, Benoit P, Fernandez F, Hagege A, Gay J, Guerot C
Service de cardiologie, hôpital Boucicaut, Paris.
Arch Mal Coeur Vaiss. 1990 Apr;83(4):537-42.
Four cases of hypertrophic obstructive cardiomyopathy diagnosed on clinical, phonomechanographic, echocardiographic and haemodynamic criteria progressing to dilated cardiomyopathy are reported. This evolution was observed over a number of years (up to 20 years) and was accompanied by a clinical aggravation in all cases with 2 deaths and atrial fibrillation in 3 of the 4 cases. The signs of intraventricular obstruction [systolic murmur, bulge on the carotid pulse tracing, systolic anterior motion of the mitral valve (SAM) and intraventricular pressure gradient] disappeared as the left heart chambers dilated with a reduction in ventricular wall motion and parietal thinning but no change in myocardial mass.
报告了4例根据临床、心音图、超声心动图和血流动力学标准诊断为肥厚性梗阻性心肌病并进展为扩张型心肌病的病例。这种演变在数年（长达20年）内被观察到，并且在所有病例中均伴有临床症状加重，4例中有2例死亡，3例出现心房颤动。随着左心腔扩张，心室壁运动减少和室壁变薄，但心肌质量无变化，室内梗阻的体征[收缩期杂音、颈动脉搏动描记图上的凸起、二尖瓣收缩期前向运动（SAM）和室内压力梯度]消失。
