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[研究腿部动脉病变和慢性静脉功能不全中血管活性药物的方法]

[Methods for studying vasoactive drugs in arteriopathy of the leg and chronic venous insufficiency].

作者信息

Franco A, Carpentier P

机构信息

Médecine interne et angiologie, CHRU, Grenoble.

出版信息

Arch Mal Coeur Vaiss. 1990 Mar;83 Spec No 2:79-82.

PMID:2111691
Abstract

Vasoactive drugs are widely prescribed in France. Over the last few years, some of these molecules have been evaluated by controlled clinical trials based on subjective assessment of their effects on the arterial or venous disease. Paraclinical investigations performed with a view to provide clinical pharmacological or physiopathological information give an indication as to the mode of action of these drugs but cannot, under any circumstances, be substituted for controlled clinical trials implying the inclusion of large patient population groups.

摘要

血管活性药物在法国被广泛使用。在过去几年中,其中一些药物已通过对照临床试验进行评估,这些试验基于对其对动脉或静脉疾病影响的主观评估。为提供临床药理学或生理病理学信息而进行的临床前研究表明了这些药物的作用方式,但在任何情况下都不能替代涉及大量患者群体的对照临床试验。

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