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[宫颈癌筛查中使用特定生物标志物的经济方面]

[Economic aspects of using selected biomarkers in cervical cancer screening].

作者信息

Rokita Wojciech, Kedzia Witold, Gaj Agnieszka, Kulig Bartosz

机构信息

Oddział Połoinictwa i Ginekologii Szpital Kielecki NZOZ Sw. Aleksandra, Kielce.

出版信息

Ginekol Pol. 2010 Oct;81(10):774-7.

Abstract

Increasing knowledge about the cervical cancer etiology, combined with the development of molecular diagnostics technology using DNA matrix and mRNA matrix, introduced a new quality in cervical cancer screening. Moving the diagnostics from the cellular level into the molecular level allowed not only to identify the existing precancerous states, but also to foresee these pathologies in the stage of cellular or molecular changes using oncogenesis biomarkers. The new diagnostic tools give hope for the improvement of effectiveness of cervical cancer screening and for a significant reduction of costs.

摘要

随着对宫颈癌病因的了解不断增加,再加上使用DNA基质和mRNA基质的分子诊断技术的发展,宫颈癌筛查有了新的质量提升。将诊断从细胞水平提升到分子水平,不仅能够识别现有的癌前状态,还能利用肿瘤发生生物标志物在细胞或分子变化阶段预测这些病变。这些新的诊断工具为提高宫颈癌筛查的有效性以及大幅降低成本带来了希望。

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