Urbancsek J, Csömör S, Benno R, Thomas R, Sztanyik L, Klaus G
Semmelweis Orvostudományi Egyetem, I. sz. Nöi Klinika.
Orv Hetil. 1990 Apr 29;131(17):905-9.
The incidence of the premature LH-rise/peak has been analysed in view to the pregnancy rate in 139 HMG and combined Buserelin + HMG cycles of an IVF-ET/GIFT program. A premature LH-rise/peak seems to be correlated with a lower pregnancy rate; therefore the cancellation of the stimulation is recommended in these cases. A gonadotropin suppression by the GnRH-analog Buserelin before and during the HMG treatment proved to be a good method to prevent a premature LH-rise/peak and to decrease the number of cancelled stimulation cycles.
针对体外受精 - 胚胎移植/配子输卵管内移植（IVF - ET/GIFT）项目中139个促性腺激素（HMG）以及布舍瑞林联合HMG周期的妊娠率，分析了过早出现促黄体生成素（LH）升高/峰值的发生率。过早的LH升高/峰值似乎与较低的妊娠率相关；因此，在这些情况下建议取消刺激。在HMG治疗前及治疗期间，使用促性腺激素释放激素（GnRH）类似物布舍瑞林抑制促性腺激素，被证明是预防过早LH升高/峰值以及减少取消刺激周期数量的一种有效方法。
