Baclofen-induced morbiliform rashes: a case series.

Baclofen is a gamma amino butyric acid (GABA) derivative that is a specific agonist at GABA-B receptors. Initially used in the treatment of spasticity, it is now being used in the treatment of alcohol dependence. Although it has several known adverse effects, incidence of rashes developing due to baclofen is very rare, and morbiliform rashes due to baclofen, an exceedingly rare adverse effect, has been reported only once before. We report a case series of 4 patients who developed morbiliform rashes after initiation of baclofen.