School of Medicine;
Can J Infect Dis Med Microbiol. 2009 Winter;20(4):112-6. doi: 10.1155/2009/763018.
Blastomycosis is an uncommon granulomatous pulmonary and extrapulmonary infectious disease caused by the thermally dimorphic fungus Blastomyces dermatitidis. Diagnosis may be delayed or difficult because of varied presentation. The characteristics of blastomycosis on computed tomographic (CT) scan of the chest are not well characterized.
The images from 34 chest CT scans from patients with confirmed pulmonary blastomycosis were retrospectively reviewed.
The most common CT findings were air bronchograms in 22 patients (65%), consolidation in 21 patients (62%), nodules (smaller than 3 cm) in 21 patients (62%) and lymph node enlargement (mediastinal and hilar nodes combined) in 12 patients (35%). Only four patients (12%) had a miliary pattern.
A specific abnormality characteristic of pulmonary blastomycosis was not identified on CT scanning. The diagnosis can only be made in the context of a high index of clinical suspicion with histological or culture confirmation.
芽生菌病是一种由热双相真菌皮炎芽生菌引起的罕见肺部和肺外肉芽肿性传染病。由于临床表现多样，诊断可能会被延误或难以确定。胸部 CT 扫描上的芽生菌病特征尚未得到很好的描述。
回顾性分析了 34 例确诊为肺部芽生菌病患者的胸部 CT 图像。
最常见的 CT 表现为 22 例（65%）空气支气管征、21 例（62%）实变、21 例（62%）结节（小于 3cm）和 12 例（35%）纵隔和肺门淋巴结肿大。只有 4 例（12%）有粟粒样表现。
在 CT 扫描上没有发现特征性的肺部芽生菌病的特定异常。只有在临床高度怀疑并经组织学或培养证实的情况下才能做出诊断。
