唾液潜血与口腔挥发性硫化物水平的关系

[Relationship between salivary occult blood and level of volatile sulphur compounds in oral cavity].

作者信息

An Yue-bang, He Lu, Meng Huan-xin, Liu Ting-ting, Liu Jian

机构信息

Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing, China.

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 2010 Jul;45(7):431-4.

PMID:21122437

Abstract

OBJECTIVE

To observe the change of the salivary occult blood after periodontal mechanical therapy, and to assess the correlations between salivary occult blood and the level of volatile sulphur compounds (VSC) in oral cavity, periodontal clinical parameters, respectively.

METHODS

Fifty patients with gingivititis, mild or moderate periodontitis were included. The level of VSC were measured by Halimeter(®) and salivary occult blood was tested by Perioscreen(®) before periodontal examination. Then full mouth plaque index (PLI), probing depth (PD), bleeding index (BI) were charted. Attachment loss (AL) of the Ramfjörd teeth were recorded lastly. Intensive periodontal mechanical therapy was conducted including oral hygiene instruction, scaling and root planing (SRP). Four weeks after SRP, the same examinations were repeated.

RESULTS

Salivary occult blood was significantly correlated with BI (r = 0.294) and PLI (r = 0.308) before periodontal therapy (P < 0.01), and also significantly correlated with VSC level (r = 0.386), PLI (r = 0.456), BI (r = 0.352), AL (r = 0.325) after therapy (P < 0.05). The improvement of VSC level [211.0 (111.0 - 389.5) × 10⁻⁹ vs 100.0 (46.3 - 165.3) × 10⁻⁹], the clinical periodontal parameters including PLI [(1.3 ± 1.0) vs (0.4 ± 0.6)], PD [(3.7 ± 1.5) mm vs (2.7 ± 0.9) mm], BI [(1.8 ± 1.2) vs (0.4 ± 0.7)] and AL [(1.0 ± 1.1) mm vs (0.1 ± 0.5) mm after the treatment was statistically significant (P < 0.001). However, standing on the viewpoint of salivary occult blood changes from positive before therapy to negative after therapy, only 80% (40/50) individuals were totally cured. VSC level in oral cavity and periodontal clinical parameters significantly decreased (P < 0.001) following the trends from strong positive, weak positive, to negative results of salivary occult blood test.

CONCLUSIONS

Salivary occult blood was correlated with VSC level in oral cavity of periodontal treated patients. It may be an objective parameter to evaluate the gingival inflammation and the efficacy of the periodontal therapy at individual level.

摘要

目的

观察牙周机械治疗后唾液潜血的变化，并分别评估唾液潜血与口腔挥发性硫化物（VSC）水平、牙周临床参数之间的相关性。

方法

纳入50例牙龈炎、轻中度牙周炎患者。在牙周检查前，用Halimeter（®）测量VSC水平，用Perioscreen（®）检测唾液潜血。然后记录全口菌斑指数（PLI）、探诊深度（PD）、出血指数（BI）。最后记录Ramfjörd牙的附着丧失（AL）。进行强化牙周机械治疗，包括口腔卫生指导、龈上洁治和根面平整（SRP）。SRP治疗4周后，重复相同检查。

结果

牙周治疗前，唾液潜血与BI（r = 0.294）和PLI（r = 0.308）显著相关（P < 0.01），治疗后也与VSC水平（r = 0.386）、PLI（r = 0.456）、BI（r = 0.352）、AL（r = 0.325）显著相关（P < 0.05）。治疗后VSC水平[211.0（111.0 - 389.5）×10⁻⁹ vs 100.0（46.3 - 165.3）×10⁻⁹]、包括PLI[（1.3 ± 1.0）vs（0.4 ± 0.6）]、PD[（3.7 ± 1.5）mm vs（2.7 ± 0.9）mm]、BI[（1.8 ± 1.2）vs（0.4 ± 0.7）]和AL[（1.0 ± 1.1）mm vs（0.1 ± 0.5）mm]在内的临床牙周参数改善有统计学意义（P < 0.001）。然而，从治疗前唾液潜血阳性变为治疗后阴性的角度来看，只有80%（40/50）的个体完全治愈。随着唾液潜血检测结果从强阳性、弱阳性到阴性的变化趋势，口腔VSC水平和牙周临床参数显著降低（P < 0.001）。