Department of Community Medicine, Faculty of Health Sciences, University of Tromso, Norway.
J Occup Environ Med. 2010 Dec;52(12):1167-72. doi: 10.1097/JOM.0b013e3181fc5e35.
The aim of this study was to assess the respiratory status in salmon-processing workers.
The study population was composed of 139 salmon workers and 214 controls. A study protocol comprised a questionnaire, spirometry, measurements of fractional exhaled nitric oxide concentration, and total and specific immunoglobulin E analyses.
Adjusted odds ratio of general respiratory symptoms ranged from 2.2 for wheezing to 3.6 for daily morning cough. Salmon workers were found to have an excess of work-related respiratory symptoms (2.9 ≤ adjusted odds ratio ≤ 13.6) and reduced lung function. Positive interaction of smoking and exposure was found for work-related upper respiratory symptoms and shortness of breath. Fractional exhaled nitric oxide concentration levels were higher in controls. None from the controls had salmon-specific immunoglobulin E, compared with 2.2% of salmon workers.
Salmon-processing workers exhibit impaired respiratory status and are more likely to be sensitized to salmon.
本研究旨在评估三文鱼加工工人的呼吸状况。
研究人群由 139 名三文鱼工人和 214 名对照组成。研究方案包括问卷调查、肺功能测定、呼出气一氧化氮浓度测定以及总免疫球蛋白 E 和特异性免疫球蛋白 E 分析。
调整后的一般呼吸道症状比值比（odds ratio，OR）范围为 2.2（喘息）至 3.6（每日清晨咳嗽）。三文鱼工人出现与工作相关的呼吸道症状（2.9≤调整 OR≤13.6）和肺功能下降的风险增加。工作相关上呼吸道症状和呼吸困难与吸烟和暴露的正交互作用有关。呼出气一氧化氮浓度水平在对照组中较高。与 2.2%的三文鱼工人相比，对照组中无人具有三文鱼特异性免疫球蛋白 E。
三文鱼加工工人的呼吸状况受损，且更易对三文鱼产生过敏反应。
