Hu Z X, Zheng Z G, Zhang X P
Department of Cardiology, China-Japan Friendship Hospital, Beijing.
Chin Med J (Engl). 1990 Jan;103(1):19-24.
A pulsed Doppler technique combined with cross sectional echocardiography was used to examine the flow velocity pattern in the pulmonary artery (PA) in 17 patients with PA hypertension documented by cardiac catheterization and in 16 healthy subjects as control. In healthy subjects the blood flow pattern in systole showed a round shape, in PA hypertension group it was either narrow triangular or intermediate. There was a significant correlation between the corrected acceleration time and mean PA pressure, the coefficient being -0.78. An improved correlation (r = -0.82) was found between acceleration time and natural log of mean PA pressure. Using PA acceleration time of 100 ms or less as a criteria resulted in a 76.5% sensitivity and a 100% specificity for detection of PA hypertension. This technique made the noninvasive estimation of pulmonary hypertension possible.
采用脉冲多普勒技术结合横断面超声心动图，对17例经心导管检查证实为肺动脉高压患者及16名健康受试者作为对照，检测肺动脉（PA）内的血流速度模式。健康受试者收缩期血流模式呈圆形，肺动脉高压组则呈窄三角形或中间形。校正加速时间与平均肺动脉压之间存在显著相关性，系数为-0.78。加速时间与平均肺动脉压自然对数之间的相关性更好（r = -0.82）。以肺动脉加速时间100毫秒或更短为标准，检测肺动脉高压的敏感性为76.5%，特异性为100%。该技术使肺动脉高压的无创评估成为可能。
