Department of Global Health Policy, School of International Health, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Bull World Health Organ. 2010 Dec 1;88(12):930-6. doi: 10.2471/BLT.10.079004. Epub 2010 Sep 3.
to estimate the prevalence and identify the determinants of non-prescription use of antibiotics for children in Mongolia.
a community-based cross-sectional survey was undertaken in 10 subdistricts in Ulaanbaatar, Mongolia's capital. We used a structured questionnaire to collect data from a random sample of 540 households with at least one child aged < 5 years. Logistic regression was used to identify factors associated with antibiotic misuse.
of 503 participating caregivers, 71% were mothers; 42.3% (95% confidence interval, CI: 37.8-46.9) of caregivers had used non-prescribed antibiotics to treat symptoms in their child during the previous 6 months. Symptoms commonly treated were cough (84%), fever (66%), nasal discharge (65%) and sore throat (60%). Amoxicillin was the most commonly used antibiotic (58%). Pharmacies were the main source (86%) of non-prescribed antibiotics. Non-prescribed use by mothers was significantly associated with keeping antibiotics at home (odds ratio, OR: 1.7; 95% CI: 1.04-2.79), caregiver self-medication (OR: 6.3; 95% CI: 3.8-10.5) and older child's age (OR: 1.02; 95% CI: 1.01-1.04). Caregivers with a better knowledge of antibiotics were less likely to give children non-prescribed antibiotics (OR: 0.7; 95% CI: 0.6-0.8).
the prevalence of non-prescribed antibiotic use for young children was high in Ulaanbaatar. Because such use leads to the spread of bacterial resistance to antibiotics and related health problems, our findings have important implications for public education and the enforcement of regulations regarding the sale of antibiotics in Mongolia.
估计蒙古儿童非处方使用抗生素的流行率,并确定其决定因素。
在蒙古首都乌兰巴托的 10 个分区进行了一项基于社区的横断面调查。我们使用结构化问卷从至少有一名 5 岁以下儿童的 540 户家庭中随机抽取了一个样本,收集数据。使用逻辑回归来确定与抗生素滥用相关的因素。
在 503 名参与的照顾者中,71%为母亲;42.3%(95%置信区间,CI:37.8-46.9)的照顾者在过去 6 个月中曾使用非处方抗生素治疗孩子的症状。常见的治疗症状是咳嗽(84%)、发烧(66%)、鼻涕(65%)和喉咙痛(60%)。阿莫西林是最常用的抗生素(58%)。药店是非处方抗生素的主要来源(86%)。母亲的非处方使用与在家中保留抗生素(优势比,OR:1.7;95%CI:1.04-2.79)、照顾者自我用药(OR:6.3;95%CI:3.8-10.5)和孩子年龄较大(OR:1.02;95%CI:1.01-1.04)显著相关。抗生素知识较好的照顾者不太可能给孩子非处方抗生素(OR:0.7;95%CI:0.6-0.8)。
乌兰巴托儿童小剂量使用抗生素的情况较为普遍。由于这种使用会导致细菌对抗生素的耐药性传播和相关的健康问题,因此我们的发现对蒙古的公众教育和抗生素销售法规的执行具有重要意义。