Braedel H U, Steffens J, Ziegler M, Polsky M S
Department of Radiologic Urology, University of Saarland, Homburg/Saar, West Germany.
Br J Urol. 1990 May;65(5):536-40. doi: 10.1111/j.1464-410x.1990.tb14804.x.
Between 1983 and 1989, 334 patients with idiopathic left-sided varicocele were referred for transfemoral sclerotherapy; 323 were adults and 11 were children. The standard site of injection of the sclerosing solution (Varicocid-Natriummorrhuat 55 mg, Benzylalkohol 20 mg) was the mid-portion of the spermatic vein. The upper third was injected only in cases where the catheter could not be negotiated further (e.g. abnormalities in the course of the spermatic vein or its drainage into the intrarenal veins). The amount of sclerosing material was predetermined fluoroscopically using contrast material. Occasionally, in cases of high catheter positioning, the Varicocid was injected fractionally. The amount injected was always between 1 and 3 ml. Of 80 patients studied 1 year later, varicoceles were still present in 3 (4%). The best results were achieved in patients with small varicoceles (Grade I), normal testicular volume and normal FSH levels; 29% showed an improvement in sperm count and 27% an increase in sperm motility, while sperm morphology improved in only 7%. The conception rate was 11%.
1983年至1989年间，334例特发性左侧精索静脉曲张患者接受了经股静脉硬化疗法；其中323例为成人，11例为儿童。硬化溶液（Varicocid-Natriummorrhuat 55毫克，苯甲醇20毫克）的标准注射部位是精索静脉中部。仅在导管无法进一步推进的情况下（例如精索静脉走行异常或其汇入肾内静脉异常）才注射上三分之一段。使用造影剂在荧光镜下预先确定硬化材料的用量。偶尔，在导管位置较高的情况下，Varicocid会分次注射。注射量始终在1至3毫升之间。在1年后接受研究的80例患者中，仍有3例（4%）存在精索静脉曲张。精索静脉曲张较小（I级）、睾丸体积正常且促卵泡激素水平正常的患者取得了最佳效果；29%的患者精子计数有所改善，27%的患者精子活力增加，而精子形态仅改善了7%。受孕率为11%。
