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社论:下消化道出血时行紧急结肠镜检查:未必如此急迫。

Editorial: Urgent colonoscopy in lower GI bleeding: not so fast.

出版信息

Am J Gastroenterol. 2010 Dec;105(12):2643-5. doi: 10.1038/ajg.2010.401.

Abstract

The role of urgent colonoscopy in lower gastrointestinal bleeding (LGIB) remains controversial. Although some studies have shown that examinations performed within 12-24 h of admission improve diagnostic yield and reduce rebleeding and surgery, others have not. In this issue of the American Journal of Gastroenterology, Laine and Shah present a randomized trial of urgent (<12 h from admission) vs. elective (36-60 h from admission) colonoscopy in 72 patients with LGIB. A total of 15% of patients with presumed LGIB were found to have upper gastrointestinal bleeding, highlighting the importance of excluding a gastroduodenal source in patients with severe hematochezia. The majority of patients with LGIB (72%) stopped bleeding spontaneously, and there were no differences in rebleeding, blood transfusions, diagnostic or therapeutic interventions, length of hospital stay, or hospital charges in patients undergoing urgent vs. elective colonoscopy. However, the limited number of patients in this study and the fact that patients in the urgent colonoscopy arm appeared to have more severe bleeding than those undergoing elective examinations make it difficult to draw conclusions regarding the utility of urgent vs. elective colonoscopy in LGIB.

摘要

在急性下消化道出血(LGIB)中,紧急结肠镜检查的作用仍存在争议。尽管一些研究表明,在入院后 12-24 小时内进行的检查可以提高诊断率并减少再出血和手术,但其他研究则没有。在本期《美国胃肠病学杂志》中,Laine 和 Shah 发表了一项针对 72 例 LGIB 患者的紧急(入院后<12 小时)与择期(入院后 36-60 小时)结肠镜检查的随机试验。在被认为患有 LGIB 的患者中,有 15%的患者被发现患有上消化道出血,这突出了在有严重血便的患者中排除胃十二指肠来源的重要性。LGIB 患者中有 72%的患者自发性停止出血,在紧急结肠镜检查组和择期结肠镜检查组之间,再出血、输血、诊断或治疗干预、住院时间或住院费用均无差异。然而,由于该研究中患者数量有限,以及紧急结肠镜检查组的患者似乎比接受择期检查的患者出血更为严重,因此难以得出关于在 LGIB 中紧急与择期结肠镜检查的效用的结论。

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